Plastic debris is known to undergo fragmentation at sea, which is accumulating in marine habitats, presence of plastic provides a potential pathway for the transfer of pollutants to organisms with uncertain consequences for their health. Fifteen water samples were collected via vertical hauls during expedition in October, 2016 throughout Santa Cruz and San Cristobal Island of Galápagos Archipelago. The collection process was carried out using 150 μm mesh manta trawl, and the samples were analyzed for plastic debris and zooplankton organisms